State-Wide Utilization and Performance of Traditional and Cell-Free DNA-Based Prenatal Testing Pathways: The Victorian Perinatal Record Linkage (PeRL) Study

In recent years, the use of combined first-trimester screening (CFTS) and cell-free DNA (cfDNA) has increased. With rise CFTS cfDNA prenatal testing, there been a dramatic decrease in number invasive diagnostic tests performed during pregnancy. this study, authors record-linkage study to obtain state-wide cfDNA, CFTS, postnatal cytogenetic data determine utilization performance different genetic pathways, as well major chromosomal abnormalities detected following low-risk or result Australia.